Camilo Rojas Selected Research

Diazooxonorleucine

1/2019	JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress.
9/2016	Discovery of 6-Diazo-5-oxo-l-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma.
4/2015	Neurological sequelae induced by alphavirus infection of the CNS are attenuated by treatment with the glutamine antagonist 6-diazo-5-oxo-l-norleucine.

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Camilo Rojas Research Topics

Disease

10	Neoplasms (Cancer) 05/2019 - 10/2005
10	Vomiting 12/2015 - 09/2006
9	Nausea 12/2015 - 09/2006
7	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2017 - 09/2007
7	Neuralgia (Stump Neuralgia) 01/2016 - 05/2003
6	Nervous System Diseases (Neurological Disorders) 01/2021 - 09/2012
6	Schizophrenia (Dementia Praecox) 05/2016 - 06/2005
4	Neuroinflammatory Diseases 01/2018 - 06/2014
4	Prostatic Neoplasms (Prostate Cancer) 12/2012 - 10/2005
3	Pain (Aches) 01/2022 - 12/2012
3	Alzheimer Disease (Alzheimer's Disease) 11/2020 - 07/2013
3	Infections 01/2020 - 06/2013
3	Brain Injuries (Brain Injury) 10/2019 - 09/2007
3	Inflammation (Inflammations) 12/2018 - 01/2014
3	Multiple Sclerosis 01/2015 - 12/2012
3	Peripheral Nervous System Diseases (PNS Diseases) 07/2013 - 12/2012
2	Neurobehavioral Manifestations 05/2016 - 01/2016
2	Psychotic Disorders (Schizoaffective Disorder) 01/2016 - 06/2005
2	Wounds and Injuries (Trauma) 06/2013 - 12/2012
1	Canavan Disease (Leukodystrophy, Spongiform) 01/2021
1	Disease Progression 10/2019
1	Anhedonia 01/2019
1	Encephalitis (Encephalitis, Rasmussen) 12/2018
1	Mental Disorders (Mental Disorder) 10/2017
1	Chorioamnionitis 10/2016
1	Hypertrophy 10/2016
1	Glioblastoma (Glioblastoma Multiforme) 09/2016
1	Colitis 08/2016
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 08/2016
1	Breast Neoplasms (Breast Cancer) 05/2016
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2016
1	Alphavirus Infections 04/2015
1	Encephalomyelitis (Myeloencephalitis) 04/2015
1	Virus Diseases (Viral Diseases) 04/2015

Drug/Important Bio-Agent (IBA)

14	Glutamic Acid (Glutamate)FDA Link 03/2017 - 08/2003
9	Glutamate Carboxypeptidase II (N-Acetylaspartylglutamate Peptidase)IBA 10/2017 - 08/2003
9	Palonosetron (Aloxi)FDA Link 12/2015 - 12/2007
5	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 11/2020 - 01/2015
5	Glutamine (L-Glutamine)FDA Link 09/2016 - 08/2013
4	Proteins (Proteins, Gene)FDA Link 10/2019 - 06/2014
4	GlutaminaseIBA 01/2019 - 09/2007
4	Serotonin (5 Hydroxytryptamine)IBA 01/2014 - 06/2005
4	Substance PIBA 08/2012 - 09/2006
3	DiazooxonorleucineIBA 01/2019 - 04/2015
3	Serine (L-Serine)FDA Link 05/2016 - 12/2011
3	Analgesics (Analgesic Drugs)IBA 01/2016 - 12/2012
3	Pharmaceutical PreparationsIBA 01/2016 - 01/2014
3	Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA 01/2014 - 06/2012
3	TachykininsIBA 01/2014 - 06/2012
3	AcidsIBA 09/2013 - 04/2004
3	LigandsIBA 12/2012 - 11/2010
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2022 - 01/2019
2	EnzymesIBA 01/2021 - 05/2019
2	ProdrugsIBA 01/2019 - 09/2016
2	netupitantIBA 12/2015 - 08/2012
2	5-HT3 Serotonin Receptors (5 HT3 Receptor)IBA 08/2014 - 01/2014
2	EmeticsIBA 01/2014 - 09/2006
2	Aprepitant (Emend)FDA Link 01/2014 - 09/2006
2	AntigensIBA 12/2012 - 12/2012
2	3- (2- mercaptoethyl)biphenyl- 2,3- dicarboxylic acidIBA 12/2012 - 12/2012
2	Sulfhydryl Compounds (Thiols)IBA 12/2012 - 05/2003
1	N-acetylaspartate (N-acetyl aspartate)IBA 01/2021
1	Aspartic Acid (Aspartate)FDA Link 01/2021
1	Acetates (Acetic Acid Esters)FDA Link 01/2021
1	aspartate N-acetyltransferaseIBA 01/2021
1	Therapeutic UsesIBA 01/2020
1	pyrenedodecanoylcarnitineIBA 10/2019
1	RNA (Ribonucleic Acid)IBA 10/2019
1	CeramidesIBA 05/2019
1	MicroRNAs (MicroRNA)IBA 12/2018
1	(R)- (11C)1- (2- chlorophenyl)- N- methyl- N- (1- methylpropyl)- 3- isoquinolinecarboxamideIBA 01/2018
1	PK 11195 (PK11195)IBA 01/2018
1	2-(phosphonomethyl)pentanedioic acidIBA 10/2017
1	CytokinesIBA 03/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2017
1	Carisoprodol (Soma)FDA LinkGeneric 10/2016
1	EndotoxinsIBA 10/2016
1	Folic Acid (Vitamin M)FDA LinkGeneric 08/2016
1	HydrolasesIBA 08/2016
1	Dextrans (Dextran)FDA Link 08/2016
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 08/2016
1	CB-839IBA 05/2016
1	GlycogenIBA 01/2016
1	N-Methylaspartate (NMDA)IBA 01/2016
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2016
1	Metformin (Glucophage)FDA LinkGeneric 01/2016
1	Amino Acids FDA Link 01/2016
1	Alanine (L-Alanine)FDA Link 01/2016
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2016
1	Neurotransmitter Receptors (Neurotransmitter Receptor)IBA 12/2015
1	rolapitantIBA 12/2015
1	AntiemeticsIBA 12/2015
1	Viral RNAIBA 04/2015
1	Cystine (L-Cystine)IBA 01/2015
1	metabotropic glutamate receptor 3 (mGluR3)IBA 01/2015

Therapy/Procedure

10	Drug Therapy (Chemotherapy) 12/2015 - 09/2006
7	Therapeutics 11/2020 - 08/2014
3	Oral Administration 01/2014 - 05/2003
1	Art Therapy 01/2020
1	Transplantation 01/2016